Omeprazole

Omeprazole is a medicine that reduces the production of stomach acid. Omeprazole belongs to the so-called proton pump inhibitors. These block the production of stomach acid by irreversible inhibition of the proton pump.

What is omeprazole used for?

Omeprazole is mainly used for stomach complaints, stomach ulcers and duodenal ulcers. It can also be used alongside other medicines that can damage the stomach. Examples include prednisone or other anti-inflammatories, often referred to as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). A specialist or GP can prescribe omeprazole.

Symptoms for which people often use the medicine include nausea, heartburn or reflux of stomach acid into the oesophagus.

What are possible side effects of omeprazole?

In practice, side effects are uncommon. If they do occur, they include gastrointestinal complaints such as diarrhoea, constipation, nausea and vomiting. Headache is also a rare side effect. In practice these side effects occur in 1-10 out of 100 people. Very rarely, in fewer than 1 out of 100 people, side effects such as dizziness, hair loss, double vision and rash occur.

Research has also shown that proton pump inhibitors reduce the absorption of vitamin B12 and can cause a vitamin deficiency over the long term. The risk of chronic kidney disease is relatively higher in people who use proton pump inhibitors for a long time. This is a brief description of the possible side effects when using omeprazole; read the full leaflet.

Where is omeprazole available?

Omeprazole has been on the international market since 1988. If prescribed, it is available as capsules and tablets under the brand names Losec, Omecat and Losecosan. Omeprazole is available from the pharmacy and drugstore.